how long do venofer side effects last

If youre sexually active and you or your partner can become pregnant, talk with your doctor about your birth control needs while youre taking Injectafer. Although a single administration of FCM frequently causes transient hypophosphatemia, a 2016 study showed that repeated treatment with FCM is associated with a high risk of developing severe and prolonged hypophosphatemia and should therefore be monitored. Many people using this medication do not have serious side effects.Severe dizziness or fainting (hypotension) may occur while you are receiving IV iron. I was surprised too but the Dr said it definitely sounds like a reaction. In one study, treatment with Injectafer was compared with that of iron thats taken by mouth. If you have questions about side effects, call your doctor. Theyll recommend how to manage your condition. Answer by DrLact: About Venofer usage in lactation. Administer Venofer in 3 divided doses, given by slow intravenous infusion, within a 28 day period: 2 infusions each of 300 mg over 1.5 hours 14 days apart followed by one 400 mg infusion over 2.5 hours 14 days later. However, since peoples bodies react so differently to drugs, they often have to change their stance on certain drugs. Patients with celiac disease (gluten intolerance). This is not a complete list of possible side effects. If you think there has been an overdose, call your poison control center or get medical care right away. Injectafer can cause low blood levels of phosphorus, which is a condition called hypophosphatemia. Injectafer infusions are given over a period of at least 15 minutes. Once you have waited for 30 minutes after the injection, you may go home, providing you are feeling well. Nausea. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. Side effects like nausea and low blood pressure are common with most iron infusions. Boxed warnings alert doctors and patients about drug effects that may be dangerous. 2023 Medicine.com All rights reserved. Venofer may cause significant hypotension (decreased blood pressure). Get emergency medical help if you have signs of an allergic reaction to Venofer: hives, rash, itching; feeling light-headed; difficulty breathing; swelling of your face, lips, tongue, or throat. And this over-activation is what may lead to an allergic reaction or a delayed allergic reaction. With slow IV injection, the drug is given as a single, slow injection into your vein. upper respiratory infection. There are currently no generic forms of either drug. Cardiovascular health: Insomnia linked to greater risk of heart attack. Common Venofer side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting, diarrhea; muscle or joint pain, back pain; pain or swelling in an arm or leg; itching; or bruising or irritation where the medicine was injected. taste impairment. US residents can call their local poison control center at 1-800-222-1222. So you wont pick up this medication from a pharmacy. generalized weakness. signs of inflammation in the lining of your stomach - pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, fever. It may also cause nervousness, restlessness, and difficulty sleeping in some people. If a person does not have an allergic response or any other unanticipated reactions, a doctor will administer the remaining iron. Best food forward: Are algae the future of sustainable nutrition? Very bad and sometimes deadly allergic side effects have rarely happened. MNT is the registered trade mark of Healthline Media. Both of theseside effectscould worsen depression and lead tolife-threateningconsequences. Those going through thismedical conditionshould speak to theircare teamfor support andguidance. For people weighing less than 50 kg, administer Injectafer in two doses of 15 mg/kg of body weight, at least 7 days apart. Talk with your doctor. Check with your pharmacist. Its responsible for carrying oxygen throughout your body. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not double the dose to catch up. Source: Wolters Kluwer Health. A variety of tests can diagnose iron deficiency anemia. What to Expect When You Get Your Whole Genome Sequenced, DNA Data Can Help You Understand Ehlers-Danlos Syndrome (EDS). This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. The potential side effects of Daxxify are nearly identical to that of Botox bruising, headaches, and droopy eyelids with one big difference: They could last longer. But its only approved for use in people with CKD who may or may not need dialysis. 12 Medicines That Could Help, List Venofer Vial side effects by likelihood and severity. endobj (See also Notes section.). Severeside effectscan lead to injury or death -drowsinesscan cause a car accident or injury when operating heavymachinery. Potential injection site discoloration has happened. Call your healthcare provider or get medical help right away if you have symptoms of an allergic reaction, including but not limited to rash, chest pain, cough, dizziness, passing out, shortness of breath, sweating or throat tightness. Generics tend to cost less than brand-name drugs. This hormone is made by your kidneys. The recommended dosing guidelines of Injectafer for treating IDA are based on patient weight, as follows: Injectafer contains ferric carboxymaltose, which is a polymer that releases iron into the body. Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when Venofer is injected. If you have iron deficiency anemia (IDA), there are certain foods you can eat that may help increase your iron levels. xmq92\Kz!yIP}2~(?c/JUCK2~o_N=>K$o/_7'Z+nRkKM^y{u|ZFh$v}]O~vfo=.GowGFodVj-[-~x]Kg~9H'%h={OX/#S|Mc~|]_2nv`wwotn/+$G[{hGrP}sbZG-RGf#l~~l|Qnccml_iPy]G\17c,yPF[28z&I'+B(?rrvi,G?}/;'?;pm>?.i42ONmk~ai_u0z9o_? Usually, when drugs may cause an immune system reaction like this, its a concern with your first dose of the drug. If you miss an appointment for your Injectafer dose, youll need to call your doctors office. For more information on the possible side effects of Injectafer, talk with your doctor or pharmacist. However, to be safe, tell your doctor or pharmacist about all prescription, over-the-counter, and other drugs you take before taking Injectafer. People with IDA have low blood levels of hemoglobin. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. If you have questions about the blood tests youll need to have done to monitor your anemia, talk with your doctor. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Here we look at how Injectafer and Feraheme are alike and different. During pregnancy, this medication should be used only when clearly needed. Headache. Youll receive doses of Injectafer from a healthcare professional at a medical facility. The actual price youll pay for either drug depends on your insurance plan, your location, and the pharmacy you use. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Side effectswill last a very long time if the cause of them is not resolved. . The signs and symptoms of anaphylaxis include dizziness or fainting, skin flushing and itchiness, difficulty breathing, rapid heart rate, low blood pressure and sudden anxiety. And this can lead to anemia, including IDA. What should I know regarding pregnancy, nursing and administering Venofer Vial to children or the elderly. The Role of Genetics in Multifactorial Disorders, The Power of DNA Testing and Predictive Medicine, A Guide to Genome Explorer (Free Version), Whole Genome Sequencing in As Little As Three Weeks, What Diseases Can Be Detected Through Genetic Testing, Breast Cancer Genetic Testing: Pros and Cons, At Home Genetic Testing for Breast Cancer, DNA Tests for Breast Cancer Genetic Testing, What to Do When Medicines Have Side Effects, Blood Type and COVID: Infection Risk and Severity, Where Can I Get My Blood Type Checked for Free, How to Find Biological Father Through DNA. Blood tests may be needed to check for unwanted effects. Innovators Monograph No, you most likely wont take Injectafer long term. Canada residents can call a provincial poison control center. Some may be a better fit for you than others. People in the study received treatment with either Injectafer or Venofer. Injectafer is approved for use in adults who either: Injectafer contains the active drug ingredient ferric carboxymaltose. Allergic reactions typically occur the first time your body is exposed to a drug. Tell your doctor if you are pregnant or plan to become pregnant. You may report side effects to FDA at 1-800-FDA-1088. Keep all regular medical and laboratory appointments. other treatments you receive, you will need to go back for several treatments with Venofer. treatment schedule in further detail. endobj Its not known if Injectafer is safe to use during pregnancy. (Hemoglobin is a protein thats found in red blood cells.). Treatment with Venofer injections can make it harder for your body to absorb iron medications you take by mouth. Some products that may interact with this drug include: vitamin products, other iron-containing products. The body cannot metabolize such a high dose fast enough, so it ends up affecting a part of the body it wasnt intended to, such as the stomach. It belongs to a class of medications called iron replacement products. intense abdominal pain. Venofer (iron sucrose) injection, USP is an intravenous (IV) form of iron, which is a key ingredient for making new red blood cells. Potential side effects that are usually mild may include, but are not limited to: Headache Nausea Dry Mouth Stomachache Dizziness Diarrhea Constipation These side effects may not impact life too much and may only be temporary. Follow your doctor's directions carefully. Injectafer contains the active drug ferric carboxymaltose, while Feraheme contains the active drug ferumoxytol. You should not be treated with this medicine if you have ever had an allergic reaction to an iron injection. It is important to get each dose of this medication as scheduled. HRT, like other medications, does have some side effects and these are thought to be quite common. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Can diet help improve depression symptoms? All rights reserved. It is given into a vein for a period of time. Keep all medications away from children and pets. An example of a drug interaction that many people are not aware of isgrapefruitjuice and statins. These effects typically last between 7 and 11 hours. Notify your healthcare provider of any irritation at the injection site. Do not share your drugs with others and do not take anyone else's drugs. But for other people, their IDA returns after treatment with Injectafer. Venofer may reduce the absorption of iron preparations taken by mouth. So the goal of IDA treatment with Injectafer is to bring your hemoglobin level back to a value thats within normal range. This is a sudden response affecting the entire body, which sometimes happens to people who are allergic to peanuts or beestings. With IDA, you have low hemoglobin levels. Talk with the doctor. If this happens to you, your doctor may recommend that you receive another treatment course of Injectafer. Symptoms of overdosage include drowsiness, mental confusion, dizziness, diarrhea and vomiting etc. Any long-term side effects/dangers from iron infusions? What Is the Cost of Whole Genome Sequencing (WGS)? Generic name: iron sucrose (injection) [EYE-urn-SOO-krose] Maximum concentrations of Injectafer are achieved within 15 minutes to 1.21 hours following administration. If needed, theyll recommend treatment, including certain medications. administered at your doctors office or an infusion center. Additional studies are ongoing to see if Injectafer is a safe and effective treatment option for these conditions. To learn about other mild side effects, talk with your doctor or pharmacist, or see Injectafers package insert. Serious side effects, which are explained in more detail below in Side effect details, include: You may wonder how often certain side effects occur with this drug. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Venofer, or with both drugs (when taken individually). Serious side effects should be reported to a physician and/or PharmD for medical advice. Its caused by your body not having enough iron, which is needed to make hemoglobin. Iron-refractory iron deficiency anemia (IRIDA) is a genetic form of anemia. Depending on your anemia symptoms, your weight changes may be different than those described here. Now I've just got mild nausea and have felt faint/dizzy a few times which is rare for me. If you have a severe allergic reaction to Injectafer after youve left the medical facility where you received your dose of the drug, call your doctor right away. Copyright 1996-2023 Cerner Multum, Inc. If you would like to report to the FDA a side effect youve had with Injectafer, you can do so through MedWatch. . Venofer (iron sucrose injection, USP) Rx Only DESCRIPTION Venofer (iron sucrose injection, USP) is a brown, sterile, aqueous, complex of polynuclear iron (III)-hydroxide in sucrose for intravenous use. Follow all instructions closely. Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. Call your doctor for medical advice about side effects. An iron infusion is a way to increase the body's iron levels quickly. These tests will help make sure Injectafer is working to treat your iron deficiency anemia (IDA). Injectafer and Feraheme have different approved uses, but theyre both used to treat IDA in certain adults. Evenbirth controlcan lead to severeside effectslike bloodclots. Injectafer and Feraheme are both brand-name drugs. In clinical trials, serious allergic reactions occurred in 0.1% to 1.5% of people taking Injectafer. If you have more questions about how Injectafer will affect your anemia, talk with your doctor. For instance, those who are taking other medications or supplements as part of home remedies may continue to suffer from the ill effects of their new medication because they dontinteract. Iron infusions are given directly into a vein. And these two doses need to be separated by at least 7 days. Or your doctor may recommend that you change your eating habits to include more iron in your diet. The information provided is not intended to replace your healthcare provider's medical advice. You may also need to monitor your blood pressure at home. Venofer pregnancy and breastfeeding warnings. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics(ACMG), an Associate of the American College of Preventive Medicine(ACPM), and a member of the National Society of Genetic Counselors(NSGC). This is not a complete list of side effects and others may occur. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Consult the product instructions and your pharmacist for storage details. Orofer S 50 Injection 1 Injection in 1 Packet 147. Before using iron sucrose, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Cancer patients who have anemia and are taking an ESA. There isnt a known interaction between Injectafer and alcohol. Then your body uses that iron to make hemoglobin and RBCs. During Injectafer treatment, your doctor will likely order blood tests. Venofer is for use in adults and children at least 2 years old. endobj Things to remember when you fill your prescription. (A generic drug is an exact copy of the active drug in a brand-name medication.) Throw away unused or expired drugs. Side effects from HRT depend on a number of factors: Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. A healthcare provider will give you this injection. Below are examples of these side effects. The factors influencing how longside effectslast may not provide the answer most are looking for, but it does explain why some people cant take certain medications because theside effectsareunbearable. Your body then uses the iron from Injectafer to make hemoglobin and new RBCs. Hemoglobin is a protein thats found inside your red blood cells. Suffering from somemedical conditionsput people at risk fordrugside effectsof medications for other health concerns. Following an LSD trip, users may experience a sort of 'comedown.'. Health careproviderscan provide information on how longside effectslast by checking amedication guide. Drug class: Iron products. Side effects: DayQuil can cause side effects such as drowsiness, dizziness, nausea, vomiting, and stomach upset. Call your doctor for medical advice about side effects. In some cases, they may even recommend that you use a drug other than Injectafer to treat your anemia. These changes could help improve your anemia on a long-term basis. For some people, after receiving one treatment course (two doses) of Injectafer, their IDA is resolved. The rest of the people switched from taking iron by mouth to taking an iron product other than Injectafer thats given by IV. Medically reviewed by Sanjai Sinha, MD. This includes people who: Usually, hypophosphatemia doesnt cause symptoms. This is why family members often have the same issues with drugs as others in theirfamily. Pain in your limbs. In the studies, peoples hemoglobin level was measured to check for improvement in their anemia. The following information is provided for clinicians and other healthcare professionals. Signs of high or low blood pressure like very bad headache or dizziness, passing out, or change in eyesight. Speak to yourhealth careprofessional for medical advice on if the dosage should bereduced. Iron is a vital mineral in the body, central to transporting oxygen around the body in the hemoglobin. Do not use Injectafer in people with a history of hypersensitivity reactions to Injectafer or any components of the drug product. Hypophosphatemia seems to mostly occur in people who are already at risk for low phosphorus levels. Heres some detail on certain side effects this drug may cause. In this group, after 35 days of treatment: In clinical studies, Injectafer was effective in treating IDA in adults with CKD who didnt require dialysis. Injectafer begins working as soon as it enters your body. Available for Android and iOS devices. TheNational Instituteof Health (NIH) and the U.S.Food and Drug Administration(FDA) monitor the side effectsof new and approved medications to ensure safety. With this condition, you also have a low hemoglobin level. Ask your doctor or healthcare provider if Venofer is the right choice for you. Once inside your body, ferric carboxymaltose releases iron into your system. Instead, youll start by receiving just one treatment course of Injectafer. TheNational Instituteof Health (NIH) and the U.S. Food andDrug Administration(FDA) monitor theside effectsof new and approved medications to ensure safety. An LSD comedown is when the mental and hallucinatory effects have worn . One study of just under 5000 HRT users found that 43% were affected. Injectafer contains the active drug ferric carboxymaltose. These lists contain examples of serious side effects that can occur with Injectafer, with Venofer, or with both drugs (when taken individually). After the infusion, you can drive yourself home and return to your usual activities. Notify your healthcare provider of all medical conditions and any medications, including supplements you are taking. Hypophosphatemia has been reported in people using Injectafer after the drug was released onto the market. In pediatric patients the most common side effects (>2%) are headache, viral respiratory tract infection, peritonitis, upset stomach, throwing up, fever, dizziness, cough, arteriovenous fistula thrombosis, hypotension and hypertension (increased blood pressure). Limited data indicate that breastmilk iron is not increased after intravenous infusion of Venofer. 2 0 obj These lists dont include all possible side effects. Dr. Brandon ColbyMDis a US physician specializingin the personalized prevention of disease through the use of genomic technologies. In the US - Call your doctor for medical advice about side effects. A delayed reaction can occur in two different ways: It can happen hours or days after you receive a drug, or it can happen after a second (or later) dose of a drug. Your healthcare provider will watch you closely for 30 minutes after each dose. (One treatment course includes two doses of the drug.) These nutrients include iron, vitamin B12, and folate. }|54U|O~?|_v;f\o^(W+/-|^)O65_)rd sm }[x[)y.z Wz?9_jV0ub,`g`s?oXOSp/Kgw$b!Vb$;IvBVR9n|\0ln=;/=,mgw@do,[";/8nJL{n}Bb-|^6[~>a_1H'^M:^vv=iM+x|+Y In Canada - Call your doctor for medical advice about side effects. Youll receive doses of either drug by a healthcare professional at a medical facility. While the side effects that occur during treatment with these drugs are increasingly well-cataloged, the long-term side effects that may result from receiving these drugs are only beginning to be studied. Joint pain. For people with certain medical implants, such as pacemakers, an MRI may pose an . Most mild side effects of Injectafer typically go away within about 30 minutes of receiving your dose of the drug. Does Venofer Vial interact with other medications? Mild side effects of Injectafer can include:*. For additional information, contact your healthcare provider. Weight changes may be due to symptoms of anemia improving. To help make sure that you dont miss an appointment for your Injectafer dose, try setting an appointment reminder on your phone. A very serious allergic reaction to this drug is unlikely, but get medical help right away if it occurs. However, Injectafer has been studied for use in children with iron deficiency anemia (IDA). They can tell you about other medications that may work well for you. Consult your doctor before breast-feeding. Cholesterolmedication may reduce the risk of a stroke but it can decrease the quality of life for some people but causingweight gain, dizziness, nausea, and musclepain. This may lead to the person needing a higher dose compared to someone who is muchsmaller. experience severe side effects, please seek medical attention right away and notify the ordering physician. Some people may also experience skin irritation from the adhesive tape and other medical equipment used during the procedure. It will take about three weeks to feel the effects but your fatigue will disappear and you will feel like a new person. Venofer may cause serious side effects including: problems with your dialysis vein access point, chest pain, severe headache, blurred vision, pounding in your neck or ears, lightheadedness, pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, and fever Get medical help right away, if you have any of the symptoms listed above. Brand-name medications usually cost more than generics. I had Venofer infusions, 2 rounds now in the span of three years. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Iron infusion benefits. This is not a list of all drugs or health problems that interact with this medicine. People with IDA have low blood levels of hemoglobin. FG Trade/E+ sia Getty Images Notify your healthcare provider if you are pregnant, or planning to get pregnant or breastfeeding. Patients with iron-deficiency anemia who are having high blood loss surgery (> 500 ml) within the next 2 months and need to replace iron quickly. SIDE EFFECTS: In adult patients, the most common side effects (2%) include diarrhea, upset stomach, throwing up, headache, dizziness, hypotension, pruritus (itching), pain in extremity, arthralgia (joint pain), back pain, muscle cramp, injection site reactions, chest pain and peripheral edema (swelling). If youre interested in finding an alternative to Injectafer, talk with your doctor. Learn about uses, cost, how it works, and more. 2. If this happens, you may need to get another treatment course of Injectafer, if your doctor recommends it for you. Injectafer and Venofer have different approved uses, but theyre both used to treat IDA in people with CKD. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Common side effects of Venofer include: muscle cramps, nausea, vomiting, stomach pain, strange taste in the mouth or decreased sense of taste, diarrhea, constipation, headache, cough, sore throat, sinus pain, congestion, back pain, joint pain, dizziness, weakness, tired feeling, anxiety, ear pain, swelling of the arms/legs, or Injectafer is approved to treat iron deficiency anemia (IDA) in certain adults with the condition. * This is a partial list of mild side effects from Injectafer. Tell your doctor about the allergy and what signs you had. Do not exceed 1,500 mg of iron per dosing course. But if they become more severe or dont go away, talk with your doctor or pharmacist. Venofer also comes as a liquid thats given by either IV infusion or a slow IV injection. reese0809 1 yr. ago. 2 Protocol for Intravenous iron sucrose - Venofer 2.1 Dosage The total cumulative dose of Venofer should be calculated using the table below. We comply with the HONcode standard for trustworthy health information. Its not known whether its safe to breastfeed while youre taking Injectafer. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. In this group, after 35 days of treatment: Effectiveness of Injectafer compared with a different IV iron product. Do not exceed 1,500 mg of iron per dosing course. But for other people, their anemia may come back after Injectafer treatment. Clinical trials showed that Injectafer is effective in increasing hemoglobin levels in people with iron deficiency anemia (IDA). Venofer 100 mg iron/5 mL intravenous solution, Venofer 50 mg iron/2.5 mL intravenous solution, Venofer 200 mg iron/10 mL intravenous solution, Select a condition to view a list of medication options. Check with your pharmacist if you have questions about the best way to throw out drugs. You may report side effects to Health Canada at 1-866-234-2345. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. chest pain. Before you receive Venofer, tell your doctor if you have low blood pressure, hepatitis, or if you have received many blood transfusions in the past. A lack of iron can lead to iron deficiency anaemia if left untreated. In the first group, some people continued taking iron by mouth, while other people took Injectafer. The drug helps increase your hemoglobin level back to a value thats within the normal range. Undergoingcancer treatmentwithradiation therapyorchemotherapy drugsmay result inhair loss, which can be devastating to somepeople. Venofer Side Effects. This includes your doctors, nurses, pharmacists, and dentists. <> The following information describes dosages that are commonly used or recommended. But for other people, doing so could lead to having too much iron in their body. 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. With anemia, you have a low level of red blood cells (RBCs) in your body. Dr. Colby is alsothe Founder of Sequencing.com and the authorofOutsmart Your Genes. Both Injectafer and Venofer belong to a class of medications called iron replacement products. Be ready to tell or show what was taken, how much, and when it happened. Knowing how longside effectslast can help with the decision on whether to use a particulardrug. Its possible that after getting two doses of Injectafer, your anemia may go away completely. Diarrhea is a common side effect of most iron replacement products, which is the group of drugs that Injectafer belongs to. If you come into contact with Red Tide, it can cause respiratory irritation, coughing, and sneezing. Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. Injectafer and Venofer can cause very similar side effects, but some different ones as well. People from different ethnic backgrounds process medications differently.

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